FBI agent Neville Flynn boards a flight from Honolulu, Hawaii to Los Angeles, escorting a key witness to testify against a mob boss at an upcoming trial. An on-board assassin releases a crate full of hundreds of deadly venomous snakes in an attempt to eliminate the witness. Flynn and a host of frightened passengers and crew must band together to survive the slithery threat.
Samuel L. Jackson
Neville Flynn
Julianna Margulies
Claire Miller
Nathan Phillips
Sean Jones
Kenan Thompson
Troy
Rachel Blanchard
Mercedes
Flex Alexander
Three G's
Keith Dallas
Big Leroy
Sunny Mabrey
Tiffany
Lin Shaye
Grace
Elsa Pataky
Maria
Bruce James
Ken
Casey Dubois
Curtis
Gerard Plunkett
Paul
Terry Chen
Chen Leong
Emily Holmes
Ashley
